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Protonitazene and other Nitazene Drugs - Frankenstein Opioids

Nitazines: Frankenstein Opioids

There are several new synthetic opioids on the streets known as “nitazines:” protonitazene, isotononitazine, and others.  These drugs are even more deadly than fentanyl, which has been credited for causing accidental overdose to become the number one killer of people aged 18 to 45 and single-handedly lowering the life expectancy in the US.


Protonitazene is a synthetic opioid drug that is chemically related to fentanyl and has potent analgesic (pain-relieving) effects. It is a novel psychoactive substance that has been sold online as a designer drug and is not approved for medical use.

Protonitazene is classified as a Schedule I controlled substance in the United States, which means that it has a high potential for abuse and no accepted medical use. It is also illegal in many other countries.

Like other opioids, protonitazene works by binding to opioid receptors in the brain and other parts of the body, which leads to pain relief, sedation, and a sense of euphoria. However, it can also cause a range of side effects, including respiratory depression, constipation, nausea, and addiction.

Because of its potency and potential for harm, the use of protonitazene is strongly discouraged, and individuals who are struggling with opioid addiction should seek help from a medical professional or addiction treatment center.

How to spot protonitazine: you really can't, it is mixed in with other drugs, or will be a powder or pill form.


Isotononitazine Isotonitazene is a potent synthetic opioid, and it is being abused for its opioidergic effects. The abuse of isotonitazene,
similar to other synthetic opioids, has been associated with adverse health effects, including numerous deaths

How to spot isotononitazine: you really can't, it is mixed in with other drugs, or will be a powder or pill form.

Xylazine - "Tranq Dope" (not an Opioid)

Xylazine is a veterinary medication that belongs to the class of drugs known as alpha-2 adrenergic agonists. It is commonly used as a sedative, anesthetic, and muscle relaxant for animals, especially in horses and other large animals.

Xylazine works by binding to alpha-2 adrenergic receptors in the brain and nervous system, which leads to sedation, muscle relaxation, and decreased pain sensitivity. It can also cause a decrease in heart rate and blood pressure.

While xylazine is not approved for human use in the United States, it has been abused as a recreational drug, often mixed with other drugs such as heroin or cocaine. The effects of xylazine use in humans can include drowsiness, confusion, disorientation, hallucinations, and respiratory depression.

Xylazine is a controlled substance in many countries and its use should be strictly limited to veterinary medicine under the supervision of a licensed veterinarian. Its misuse or abuse can be dangerous and even fatal.

How to spot xylazine: you really can't, it is mixed in with other drugs, or will be a powder or pill form.

Contact the Opioid Addiction Treatment Experts in San Diego

If you or a loved one are struggling with opioid addiction, contact us or call (619) 452–1200 today and a recovery expert will help you in find the best residential or outpatient addiction treatment program to fit your needs.

Located in San Diego, Confidential Recovery's outpatient rehab center provides convenient access—both weekdays and weeknights— to world-class alcohol and drug addiction treatment.

Programs at our outpatient addiction treatment center in San Diego are made up by the most effective and 'state-of-the-art' evidence-based practices. Because Confidential Recovery has reasonable rates for 'out of pocket' patients and also accepts many health insurance plans, our expert care and clinical services are within reach for many  people who need addiction counseling and related alcohol and drug rehab services.

Confidential Recovery is a great option for continued treatment and support after discharging from a residential addiction program. Confidential Recovery can also a perfect beginning for those clients who are “higher-functioning” and don’t wish to do residential treatment, are trying sober living, private therapy, working, or have parenting responsibilities.

If you have questions about the process of getting help for a substance use disorder, call us at (619) 452–1200 to discuss the matter privately with our intake counselors.





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Scott H. Silverman
CEO / Founder
Scott found himself "hitting bottom" in 1984 and accepted that he needed help for his problem and pursued treatment and long-term recovery. After pursuing his own recovery, Scott dedicated his life to helping others who struggle with the same mental health and addiction issues that caused him so much pain. Scott has made an indelible mark on the lives of many in San Diego. He has been on KUSI dozens of times to raise awareness about the dangers that we face, and to speak a message of recovery.